| Rank | City | Location | Pop. | Rank | City | Location | Pop. |
| ||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Rome | Lazio | 2,722,907 | 11 | Venice | Veneto | 270,055 | |||
| 2 | Milan | Lombardy | 1,294,797 | 12 | Verona | Veneto | 265,795 | |||
| 3 | Naples | Campania | 963,522 | 13 | Messina | Sicily | 243,315 | |||
| 4 | Turin | Piedmont | 909,193 | 14 | Padua | Veneto | 211,632 | |||
| 5 | Palermo | Sicily | 659,623 | 15 | Trieste | Friuli-Venezia Giulia | 205,466 | |||
| 6 | Genoa | Liguria | 611,556 | 16 | Taranto | Apulia | 194,042 | |||
| 7 | Bologna | Emilia-Romagna | 374,561 | 17 | Brescia | Lombardy | 190,809 | |||
| 8 | Florence | Tuscany | 365,744 | 19 | Reggio Calabria | Calabria | 185,602 | |||
| 9 | Bari | Apulia | 320,676 | 18 | Prato | Tuscany | 185,193 | |||
| 10 | Catania | Sicily | 296,816 | 20 | Modena | Emilia-Romagna | 181,704 | |||
| 2008 ISTAT estimates | ||||||||||
According to Fondazione Censis (Convivere nelle mega cities, in Rapporto annuale 2008, pp. 19–20-21-22-23.[29]) the largest Metroplexs in Italy are:
| N° | Metroplex/ Metropolitan area | Population | Area (in km²) | Density (people/km²) |
|---|---|---|---|---|
| 1 | Milan metropolitan area (Lombardy mega region) | 8.047.125 | 8.362,1 | 965,6 |
| 2 | Naples metropolitan area–Salerno | 4.996.084 | 3.841,7 | 1.300,5 |
| 3 | Rome metropolitan area | 4.339.112 | 4.766,3 | 910,4 |
| 4 | Venice–Padova–Verona (Veneto mega region) | 3.267.420 | 6.679,6 | 489,2 |
| 5 | Bari–Taranto–Lecce (Low adriatic linear system) | 2.603.831 | 6.127,7 | 424,9 |
| 6 | Rimini–Pesaro–Ancona (High adriatic linear system) | 2.359.068 | 5.404,8 | 436,5 |
| 7 | Turin metropolitan area | 1.997.975 | 1.976,8 | 1.010,7 |
| 8 | Greater Bologna–Piacenza | 1.944.401 | 3.923,6 | 495,6 |
| 9 | Florence–Pisa–Siena | 1.760.737 | 3.795,9 | 629.8 |
| 10 | Messina–Catania–Siracusa (Eastern Sicilian linear system) | 1.693.173 | 2.411,7 | 702,1 |
